PGS: a four-letter word?

Self-report: psychology's four-letter word.

Self-report continues to be one of the most widely used measurement strategies in psychology despite longstanding concerns about its validity and scientific rigor. In this article, the merits of self-report are examined from a philosophy of science perspective. A framework is also provided for evaluating self-report measures. Specifically, four issues are presented that can be used as a decisio...

Microsoft Word - Welcome Letter

The electron spin properties are promising for future spin-driven applications. Silicon, the major material of microelectronics, also appears to be a perfect material for spintronic applications. The peculiarities of the subband structure and details of the spin propagation in ultra-thin silicon films in presence of the spin-orbit interaction and strain are investigated. The application of shea...

Zero Is ot a Four Letter Word: Studies in the Evolution of Language

We examine a model genetic system that has features of both genetic programming and genetic regulatory networks, to show how various forms of degeneracy in the genotype-phenotype map can induce complex and subtle behaviour in the dynamics that lead to enhanced evolutionary robustness and can be fruitfully described in terms of an elementary algorithmic “language”. DIAS preprint DIAS-STP-04-19 T...

Letter-, Word- and Mind-Blindness

Who Benefits From PGS?

Whilst new generation sequencing techniques of blastocyst biopsies give rapid response times and are more accurate, we question whether counting chromosomes can lead to an improvement in pregnancy rates and if the cost of trophectoderm biopsy outweighs the benefit in PGS. NGS does not define embryo viability or health, as it does not guarantee that genes are free from DNA breaks/errors, or that...